New breakthrough to reverse hair greying

New breakthrough to reverse hair greying

03 April 2019, 13:10 - 13:40

Technical Seminars Theatre 3

Free radicals play a critical role in hair whitening, leading to decreasing melanogenesis in hair follicle and shrinking of melanocytes pool. By deciphering the mechanisms involved in biological hair pigmentation, we designed Darkenyl™, a combination of molecules protecting hair follicle melanocytes from ROS, activating bulge stem cells enabling the pro-duction of new melanocytes and reactivating entire melanogenesis pathway.

Under oxidation-mediated hair greying conditions, we evidenced a global protection of melanocytes and activation of antioxidant defences related to reduction of ROS. At clinical level, volunteers showed significant hair repigmentation: more than 3 times less white hair within 4 months vs placebo.


  • Morgane De Tollenaere


    Skin Biology Scientist

    Givaudan Active Beauty

    Morgane is a biotechnology engineer from Ecole de Biologie Industrielle in Cergy. She has 4 years experienced in active ingredients industry in which...

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