How to assess the skin sensitisation potential of personal care formulations?

How to assess the skin sensitisation potential of personal care formulations?

17 April 2018, 14:40 - 15:10

Technical Seminars Theatre 2
Language:
English

With the constant increasing of allergic contact dermatitis, the skin sensitising potential evaluation of new compounds is important. Many alternative methods are validated or currently under validation by EURL ECVAM. These methods, intended for the evaluation of chemicals, cannot be used for formulated products. THOR’s approach is the development of an in vitro method (3D co-culture) to assess the skin sensitising potential of formulations as a whole, rather than using toxicological data on individual components. This modeling enables solubility problems to be overcome and the cutaneous bioavailability, absorption and metabolism of a personal care product to be taken into consideration.

Contributors

  • Sophie Catoire

    Speaker

    Toxicology In Vitro Manager

    THOR Personal Care

    Sophie Catoire has a master’s degree in Cell Biology and Animal Physiology from the University of Paris XII. From 1998 to 2007 she worked as an In...

We use cookies to operate this website and to improve its usability. Full details of what cookies are, why we use them and how you can manage them can be found by reading our Privacy & Cookies page. Please note that by using this site you are consenting to the use of cookies.